Significats de cytoplasmic yap en anglès

In its phosphorylated form, cytoplasmic YAP is sequestered in an inactive state.

Finally, we found that cytoplasmic YAP positively regulated the activity of the small GTPase CDC42, deletion of which caused severe defects in endothelial migration.

Patient-derived disease models including neural progenitor cells and cerebral organoids showed that loss of NUAK2 activity led to decreased Hippo signaling via cytoplasmic YAP retention.