Significats de ddr2 en anglès

The functional effects of novel DDR2 mutants were confirmed by in vitro assays.

Results: We identified novel somatic mutations of DDR2 in two of the 100 SCC samples studied.

DDR2 mutations on exons 6, 15, 16, and 18 were analyzed by Sanger sequencing of formalin-fixed, paraffin-embedded tissue samples.

In addition, we showed that each of the novel DDR2 mutations were located in a kinase domain and induced an increase in cell proliferation rate.

Studying the DDR2 mutations in patients with SCC of the lung would advance our understanding and guide the development of therapeutic strategies against lung cancer.

Furthermore we found potentially targetable DDR2 mutations at a frequency of 3% in both adenocarcinomas and squamous cell carcinomas.

It's also got 512 MB of DDR2 RAM and an integrated Adreno 220 graphics processing unit to render 1080p high-definition video.

If you need more than the standard 64MB of DDR2-SDRAM memory, a side panel opens for easy access to the upgrade slot.

The expression of the mutant DDR2 induced activation of DDR2 by the collagen ligand and caused enhanced cell growth and tumor progression.

Conclusion: Our results suggest that a mutation in DDR2 occurs naturally with a frequency of about 2% in Korean lung SCC patients.