Significats de dendrimer en anglès

LDH assay was used to evaluate the cytotoxicity of the dendrimer and conjugates.

This Account reports the synthesis and characterization of dendrimer-encapsulated metal nanoparticles and their applications to catalysis.

Stability, antioxidant activity and collagen cross-linking activity of the natural product and its dendrimer analogues were compared.

The size of such particles depends on the number of metal ions initially loaded into the dendrimer.

The synthesis of a water-soluble polyglycerol dendrimer with two orthogonal functional groups at the core is reported.

The most active hexavalent dendrimer exhibited affinity three orders of magnitude higher than that of standard L-fucose.

The conjugation of fluorescent pH indicators to the dendrimer scaffold led to an enhancement of their sensing performances.

This first-generation dendrimer-based product was shown to be safe to the vaginal and rectal microenvironments with repeated daily use.

Extended transgene expression after DNA-dendrimer complex delivery from the scaffolds in comparison to direct delivery to cells was observed.

The inhibition of cancer growth by the dendrimer-Ara-C and PEG-Ara-C conjugates was evaluated in A549 human adenocarcinoma epithelial cells.

Principal findings: We present a novel dendrimer-based architecture leading to multifunctional sensing elements that can overcome many of these problems.

In this study a DNA-dendrimer complex embedded in a cross-linked collagen scaffold was investigated as a reservoir for non-viral delivery.

Substrate binding was correlated with the total number of histidines per dendrimer, with an average of three histidines per substrate binding site.

In PBS, while most of the drug is released from PEG-Ara-C, the dendrimer continues to release the drug in a sustained fashion.

The N-terminus of the dendrimer was further modified with an aminooxy group in order to conjugate LyP-1 and ARAL peptides bearing a ketone.

The present review compiles the recent advances in dendrimer-mediated drug and gene delivery to tumors by passive and active targeting principles with illustrative examples.