Significats de deplete cells en anglès

We further observed that Rab7 activity was inhibited in Numb- depleted cells.

This unexpected result reflects a more dynamic and mobile junctional actin in EEF1A- depleted cells.

We have also shown that mitochondrial DNA- depleted cells are insensitive to DIM to induce PCD.

Girdin- depleted cells displayed scattering and impaired E-cadherin-specific cell-cell adhesion.

Notably, inhibition of cell migration in SPARC- depleted cells was rescued by expression of a SLUG transgene.

Importantly, IS formation is impaired in spectrin- depleted cells.

Consistently, the stemness properties and metastasis can be attenuated by further knockdown of EpCAM in CK18- depleted cells.

Scanning electron microscopy of Rab11- depleted cells showed high densities of virus particles apparently stalled in the process of budding.

Furthermore, we show that simple aldehydes, known to cause leukemia in FA-deficient mice, induce DNA:RNA hybrids in FA- depleted cells.

Ultrastructural examination of the assembly site in HCMV-infected STX3- depleted cells showed fewer mature virions and more viruses undergoing final envelopment.

We used time-lapse analysis to demonstrate defects in the motility of liprin-a1- depleted cells that include a striking instability of the lamellipodia.

Exogenous expression of Myc-MSR1 restores TLR3 signaling in MSR1- depleted cells with subsequent induction of an antiviral state.

We show that hSSB1 depleted cells contain less BLM protein and that this deficiency is due to proteasome mediated degradation of BLM.

However, IGF-I receptor signaling was significantly reduced in the mitochondria- depleted cells, which suggested that maintaining normal IGF-I receptor signaling in cardiomyocytes required functioning mitochondria.

We provide evidence that bi-nucleation in MICAL-L1- and EHD1- depleted cells is a consequence of impaired recycling endosome transport during late cytokinesis.

CSN5- depleted cells exhibited enhanced activation of the PI3 kinase-Akt pathway, and chemical inhibition of this pathway reduced the level of senescence.