Significats de deregulate cell en anglès

Loss of VHL has been reported to affect cell proliferation by deregulating cell cycle-associated proteins.

While direct targeting of MYC is difficult, specific genetic vulnerabilities of MYC- deregulated cells could be exploited to selectively inhibit their growth.

Deregulated cell division is a hallmark of cancer, but whether tumor cells become dependent on specific mitotic mechanisms is not known.

Pan-cancer analysis showed that head and neck squamous cell carcinoma (HNSCC) ranks amongst the top four cancers showing deregulated cell cycle genes.