Significats de dermal adipocytes en anglès

Here, we isolated dermal adipocytes and characterized dermal fat at the cellular and molecular level.

In addition, manipulation of dWAT highlighted an important role for mature dermal adipocytes for hair cycling and wound healing.

The fate of the mature dermal adipocytes and the origin of the rapidly reappearing dermal adipocytes at different stages remain unclear.

Together with dWAT's dynamic responses to external stimuli, we established that dermal adipocytes are a distinct class of white adipocytes with high plasticity.

By combining pulse-chase lineage tracing and single-cell RNA sequencing, we observed that mature dermal adipocytes undergo dedifferentiation and redifferentiation under physiological and pathophysiological conditions.

We discuss and speculate on potential roles of dermal adipocytes in cutaneous biology with an emphasis on communication during hair follicle growth and wound healing.