Significats de diabetic epc en anglès

In the current study, miR-31 expression was compared between normal and diabetic EPCs.

The aim of this study was to investigate how miR-31 regulates diabetic EPC function.

In diabetic EPCs, elevated glucose level was found to up-regulate miR-31 expression, which in turn enhanced the malfunction and death of EPCs.

Finally, diabetic EPC depleted of endogenous p53 do not undergo to senescence-growth arrest and acquire the ability to form tube-like structures in vitro.

A remarkable elevation in miR-31 expression was found in diabetic EPCs, and this elevated expression resulted in suppressed cell proliferation under high glucose.