Encara no tenim significats per a "diffuse ssc".
1Our findings do not provide evidence that MTX is significantly effective in the treatment of early diffuse SSc.
2We investigated the expression of integrins and CD44 on skin fibroblasts from patients with limited and diffuse SSc.
3Patients with early, diffuse SSc are the best candidates for experimental therapies intended to modify the overall disease process.
4Methods: Peripheral blood and skin biopsy specimens were collected from control subjects and patients with limited or diffuse SSc.
5This study was undertaken to examine the efficacy of methotrexate (MTX) in improving the skin and other disease parameters in early diffuse SSc.
6Conclusion: Elevated PAP are common in both limited and diffuse SSc disease, occurring in 21% of limited and 26% of diffuse SSc patients.
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