Significats de distal enhancers en anglès

Outside of promoter regions, distal enhancers play a major role in the cell type-specific regulation of gene expression.

Because promoter- distal enhancers are key to cell fate decisions, we analyzed enhancer landscapes during mononuclear phagocyte development in vivo.

Distal enhancers characterized by the H3K4me(1) mark play critical roles in developmental and transcriptional programs.

Distal enhancers have emerged as key regulatory elements that acquire histone modifications in a cell- and species-specific manner, thus enforcing specific gene expression programs.