Biochemical modification of drugs or foreign compounds by living organisms.
1 A2780 ovarian cells neither catalysed drug metabolism nor contained these drug transporters.
2 During the inflammatory response, intrahepatic cholestasis and decreased drug metabolism are frequently observed.
3 CCRP appears to be involved in various hepatic regulations far beyond CAR-mediated drug metabolism .
4 Expression data were compared to changes in conventional clinical chemistry parameters and drug metabolism activities.
5 Genetic variation in genes encoding cytochrome P450 enzymes has important clinical implications for drug metabolism .
6 Here, we extend our analysis to drug metabolism enzymes.
7 A model to study hepatic and intestinal drug metabolism in the dog has been evaluated.
8 However, the inhibition of drug metabolism in DTP vaccine-treated mice was similar in all three groups.
9 However, HF-iPS efficiently induced the generation of HLCs that expressed hepatocyte markers and drug metabolism - related genes.
10 Additionally, it has long been appreciated that exposure to drug metabolism - inducing xenobiotics can impair immune function.
11 After chronic intramuscular administration FK inhibits drug metabolism .
12 O'Malley was the first researcher to write a paper on the effect of ageing on drug metabolism .
13 Enzymes involved in drug metabolism are genetically polymorphic, meaning that their activities differ depending on certain genotypes.
14 Primary human hepatocytes (PHHs) are an essential tool for modeling drug metabolism and liver disease.
15 Tumors were analyzed for mRNA expression and polymorphisms in genes involved in drug metabolism and DNA repair.
16 Conversely, little is known about the role of this pathway in drug metabolism regulation in human liver.
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