Significats de dysfunctional hdl en anglès

Thus, dysfunctional HDLs could be an important biomarker of accelerated atherosclerosis in lupus.

One possible mechanism for the formation of dysfunctional HDL is the oxidation of its components.

Dysfunctional HDL has been identified in animal models and humans with chronic inflammatory diseases including atherosclerosis.

The authors of recent studies have shown that infection, inflammation, diabetes, and coronary artery disease are associated with dysfunctional HDL.

An increased HDL-C with the decreased PON1 activity may bring the concept of dysfunctional HDL into question in the pathogenesis of AD.

Conclusions: Our observations indicate that myeloperoxidase may contribute to the generation of dysfunctional HDL with impaired ABCA1 efflux capacity in humans with atherosclerosis.

In animal models and perhaps in humans, dysfunctional HDL can be improved by apoA-I mimetic peptides that bind oxidized lipids with high affinity.