Similar relations were observed with the use of NAFLD with normal or elevated ALT levels.

However, the role of elevated ALT levels in subjects with overt DM2 has yet not been explored.

Conclusions: More VAT and less lower trunk SAT are associated with elevated ALT, which likely reflects the presence of steatosis.

HCV infection and having more VAT or less lower trunk SAT are independently associated with elevated ALT in HIV infection.

Elevated ALT levels are associated with insulin resistance, and subjects with NAFLD have features of the metabolic syndrome that confer high-risk cardiovascular disease.

Significant associations with the anti-HCV carrier status were: blood transfusions, retrospective finding of elevated ALT and duration of dialysis treatment, independently of transfusions.

A total of 83 of 210 HBsAg-positive donors with elevated ALT levels were referred and 66 received antiviral treatment.

Statistically significant associations with the anti-HCV carrier status were duration of haemodialysis treatment, blood transfusions, and the finding of abnormally elevated ALT on retrospective analysis.

Initially elevated ALT levels had normalized in 10 of 14 patients by the end of follow-up (median 12 months, range 3-24 months).