Significats de endogenous ligand en anglès

D-Serine appears to be the endogenous ligand for the glycine site of NMDA receptors.

Apelin is a vasoactive peptide identified as the endogenous ligand of an orphan G protein-coupled receptor called APJ.

Here we describe the cloning of a neuropeptide receptor from Lymnaea and the isolation of an endogenous ligand.

Its endogenous ligand is unknown.

Although these data suggest a role for central Y4 receptors, the endogenous ligand for this receptor has yet to be clearly established.

Allosteric modulators that interact with sites topographically distinct from the endogenous ligand-binding site offer a number of advantages over their competitive counterparts.

Results: Utilizing the data available in the Open Targets platform, potential G-protein coupled receptor and endogenous ligand disease association pairs were systematically identified.

These differences were apparently not due to prior receptor occupancy by endogenous ligand, but may reflect activation of the placental renin-angiotensin system and receptor down-regulation.

Candidate endogenous ligands for the CB2 receptor have also been described.

The open face of the metal coordination sphere opposite the three endogenous ligands participates directly in the reaction chemistry.

Knowledge is limited regarding the diversity and identity of GPCRs that are activated by endogenous ligands and that native cells express.

Riboswitches are non-coding RNA structures located in messenger RNAs that bind endogenous ligands, such as a specific metabolite or ion, to regulate gene expression.

Activation of the immune response is a tightly regulated, coordinated effort that functions to control and eradicate exogenous microorganisms, while also responding to endogenous ligands.

C4BP is a large oligomeric plasma protein that binds activated complement factor C4b and other endogenous ligands as well as microorganisms.