Significats de epigenetic dysregulation en anglès

Furthermore, we showed that epigenetic dysregulation with age is a highly tissue-dependent phenomenon.

Further investigation is warranted into the roles of epigenetic dysregulation in TC development and its potential for targeted therapy.

Our results suggest that epigenetic dysregulation of cellular processes relevant to STAT1-dependent cellular differentiation may be intimately involved in breast carcinogenesis.

Arsenic exposure increases the risk of cancer and other chronic diseases, and one potential mechanism of arsenic toxicity is epigenetic dysregulation.

An increasing body of evidence suggests that epigenetic dysregulation is frequent in MAFLD, and orchestrates many aspects of its development and progression.

Given that epigenetic dysregulation is a known driver of malignancy, vitamin C may play a novel role as an epigenetic anticancer agent.

Although an attractive candidate for mediating transcriptional dysregulation, the contribution of epigenetic dysregulation to these progressive changes in cellular physiology remains unclear.

Our findings define a strong association between global genetic and global epigenetic dysregulation in mesothelioma, rather than a discrete, local coordination of gene inactivation.

Epigenetic dysregulation is an important feature for cancer initiation and progression.

Background: Epigenetic dysregulation is involved in the etiology and progression of various human diseases.

Epigenetic dysregulation has emerged as an important mechanism in cancer.

Epigenetic dysregulation plays a profound role in the pathogenesis of hematological malignancies, which is often the result of somatic mutations of chromatin regulators.