Conversely, inactivation of the ErbBreceptors reduces the expression levels of Survivin.
2
Several recent evidences suggest that NRG1 and their ErbBreceptors are involved in ALS.
3
Therefore, our results do not support a role for ErbBreceptors as auto-antigens in iMG patients.
4
We describe a new approach that directs ErbBreceptor interactions, resulting in biased signaling and phenotypes.
5
Activation of ErbBreceptor and downstream signaling molecules were observed in neurites only after heregulin stimulation.
6
Distributions of ErbBreceptors on membranes of SKBR3 breast cancer cells were mapped by immunoelectron microscopy.
7
ErbBreceptors not only function in cancer, but are also key developmental regulators in the nervous system.
8
As a biological system we examine signaling mediated ErbBreceptor family as the current literature is very controversial.
9
This review aims to compile the current knowledge on the functions of ErbBreceptors in physiology and physiopathology of the biliary epithelium.
10
Neuregulins comprise a family of epidermal growth factor-like ligands that interact with ErbBreceptor tyrosine kinases to control many aspects of neural development.
11
The ErbBreceptor family is dysregulated in many cancers, and its therapeutic manipulation by targeted antibodies and kinase inhibitors has resulted in effective chemotherapies.
12
Increasing evidence indicates that ErbBreceptor-mediated signaling plays a major role in the control of Schwann cell-axon communication and myelination in the peripheral nervous system.