Significats de erythrocyte invasion en anglès

Background: The rapid process of malaria erythrocyte invasion involves ligand-receptor interactions.

These results indicate that antibody alone is not sufficient to interfere with erythrocyte invasion.

Taken together, PypPK1 has an important role for both erythrocyte invasion and exflagellation center formation.

However, it is also a receptor for erythrocyte invasion by the malarial parasite Plasmodium falciparum.

This expression pattern is consistent with commitment to sexual differentiation prior to merozoite release and erythrocyte invasion.

Using real-time imaging of invasion, we established that heparin-like molecules block early, and essential, events in erythrocyte invasion by merozoites.

The observation that apparently host-protective merozoite antigens are not essential for efficient erythrocyte invasion has important implications for vaccine design.

These proteins are thought to play a role in erythrocyte invasion by the extracellular merozoite and are important vaccine candidates.

Immunoglobulin G against P. vivax antigens from both immune animals and human malaria patients inhibited the erythrocyte invasion by P. knowlesi.

However, we also identify a strikingly high proportion of species-specific transcripts in late schizonts, possibly associated with the specificity of erythrocyte invasion.

The fact that EBA-175 has such a universal and yet susceptible role in erythrocyte invasion clearly supports its inclusion in a multivalent malaria vaccine.

In the blood stage, ΔpPK1 parasites were able to egress from erythrocytes similar to wild type parasites; however, erythrocyte invasion efficacy was significantly reduced.

During erythrocyte invasion, merozoites are directly exposed to the host humoral immune system making the blood stage of the parasite a conceptually attractive therapeutic target.

The presence of these blocking antibodies also completely abrogates the inhibitory effect of mAb 12.8 on erythrocyte invasion by the parasite in vitro.

Erythrocyte invasion by malaria parasites is a complex multistep process involving parasite and erythrocyte receptors.