Significats de evolutionary conservation en anglès

Finally, phosphorylation sites were examined for phosphorylation-specific motifs and evolutionary conservation.

This implies ~200 million years of evolutionary conservation of the underlying immune mechanism.

Pathogenicity of these variants is supported by co-segregation and in silico analyses and evolutionary conservation.

However, the multiplicity of CD3 components and their evolutionary conservation suggest that they serve distinct functions.

The important role of CpG islands in gene transcription strongly suggests evolutionary conservation in the mammalian genome.

Finally we apply it to viral genomic data to identify regions of evolutionary conservation within influenza and rotavirus.

We also show that the predictions can be further improved by combining PASE with information about evolutionary conservation.

Taken together, our data map novel DMRs in the human genome, their evolutionary conservation, and relation to gene expression.

The quantitative model previously proposed for origin activation in X. laevis can be generalized to explain this evolutionary conservation.

These systematic measurements suggest that evolutionary conservation in the consensus sequence is driven by maintenance of the cleavage rate.

A sequenced and annotated genome has revealed a large degree of evolutionary conservation in comparison to the human genome.

We found evolutionary conservation of a leader sequence, a single C-terminal glycosylation site, collagen-binding residues, and four specific conserved PEDF peptides.

Sequence alignment and evolutionary conservation analysis of amino acids identified a metal-permeation pathway of Nrat1 centered at the metal binding site.

High evolutionary conservation of frataxin across species has enabled the development of disease models of FRDA in various unicellular and multicellular organisms.

Co-localized noisy gene pairs exhibit lower evolutionary conservation of their adjacent genome locations, suggesting that their shared transcriptional background may be disadvantageous.

SPRN was initially described in zebrafish; however, the strong evolutionary conservation led to the hypothesis that SPRN might be the ancestral prion-like gene.