Significats de exocrine insufficiency en anglès

We included studies reporting on pancreatic exocrine insufficiency in patients with pancreatic or periampullary cancer.

Background: Choosing the optimum pancreatic enzyme replacement therapy for patients with exocrine insufficiency remains a problem.

Data on patient demographics, type of pancreatic resection, diagnostic test, and occurrence of pancreatic exocrine insufficiency were extracted.

Except for one patient who required pancreatic enzyme supplements for 8 months, no other patient had pancreatic exocrine insufficiency.

Prevalence of pancreatic exocrine insufficiency was calculated before and after pancreatic resections and in patients with locally advanced pancreatic cancer.

Conclusion: Pancreatic exocrine insufficiency is diagnosed in approximately half of all patients scheduled to undergo resection for pancreatic or periampullary cancer.

In addition, by possibly decreasing the likelihood of post-operative pancreatic ductal stenosis, it has the potential to reduce post-Pancreatoduodenectomy pancreatic exocrine insufficiency.

Pancreas atrophy was observed in 5 of 6 probands, and pancreas exocrine insufficiency was observed in 6 of 7 probands.