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Adults with recurrent GBM who failed prior standard therapy were eligible.
2
Unprompted, 17 of the men described one to four failed prior attempts to become circumcised.
3
Eighteen women with estrogen receptor-positive tumors had failed prior hormonal manipulation or had metastatic breast cancer at initial diagnosis.
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Results: Of 1,156 cases 168 patients underwent repeat urethroplasty after at least 1 failed prior urethroplasty.
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Two or more failed prior urethroplasties and comorbidities associated with urethral stricture disease were associated with an increased risk of repeat urethroplasty failure.
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The companies said 58 percent of patients who failed prior treatment with chemotherapy as well as Campath responded to Arzerra, also known as ofatumumab.
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Endocyte's partner Merck & Co Inc is conducting a late-stage study of the drug, vintafolide, in patients with ovarian cancer who have failed prior treatment.