Findings: Hydroxychloroquine disrupt lipid rafts similar to local and generalanesthetics.
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Sevoflurane, one of the most used generalanesthetics, is widely used in clinical practice all over the world.
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Background: Anesthesiologists can best decide whether to use desflurane based on the magnitudes of its effects compared to other generalanesthetics.
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While not sufficiently effective as generalanesthetics for the modern operating theater, all were effective enough to become popular in dentistry.
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Conclusions: We conclude HCQ is an anesthetic-like compound that disrupts GM1 lipid rafts similar to propofol and other local or generalanesthetics.
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Background: The ability of generalanesthetics to suppress somatomotor responses to surgical incision and other noxious stimuli is of particular clinical relevance.
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Conclusions: We show that Mdivi-1 likely plays a protective role against certain harmful effects of generalanesthetics on primary rat neuronal cultures.
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Generalanesthetics (GAs) are central nervous system depressants that render patients unresponsive to external stimuli.
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Generalanesthetics (GAs) have transformed surgery through their actions to depress the central nervous system and blunt the perception of surgical insults.