Co-writer and actor in Hungry Mile Theatre company's production of Citizen Gef.

Stiffness-dependent enhancement of inflammation was associated with increased expression of Rho activator, GEF-H1.

We show here that the Rho family GEF Vav2 plays a key role in this process.

The possible use of dominant negative ras-specific GEFs as a tool to down-regulate tumor growth is discussed.

These studies demonstrate that siRNAs are an ideal research tool for the assignment of Rho GEF function in vivo.