Significats de hepatic metabolism en anglès

The significantly regulated cCYPs suggested its potential role in hepatic metabolism.

These results suggest an extensive hepatic metabolism and biliary excretion of cabazitaxel in humans.

ASPM possesses low oral bioavailability due to extensive hepatic metabolism.

The majority of the absorbed nicotine is rapidly converted to cotinine during first-pass hepatic metabolism.

Reduction of inflammation may improve the clinical outcome for patients receiving chemotherapeutic agents that undergo hepatic metabolism.

We speculate that the estrogen component of HRT has beneficial effects on hepatic metabolism through various pathways.

Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which may contribute to hyperlipidemia and obesity.

The increased Clo in pregnancy is assumed to be due to enhanced hepatic metabolism of the drug.

Abstract Anticonvulsants that induce hepatic metabolism increase clearance of oral contraceptive hormones and thereby cause contraceptive failure.

These results indicate extensive hepatic metabolism of brimonidine and provide evidence for aldehyde oxidase involvement in brimonidine metabolism.

It is concluded that the greater metoprolol clearance during pregnancy results from increased hepatic metabolism of the drug.

It suggests that intestinal absorption, not hepatic metabolism is responsible for the reduced Clop-AM exposure in T2DM rats.

These results indicate that praliciguat had rapid absorption, high bioavailability, extensive tissue distribution, and elimination primarily via hepatic metabolism.

Here, we show that CR engages RNA processing of genes associated with a highly integrated reprogramming of hepatic metabolism.

Unfortunately, cellular and animal models that accurately recapitulate these inborn errors of hepatic metabolism in the laboratory have been lacking.

Patients with DILI caused by medications with or without preponderant hepatic metabolism did not differ in clinical characteristics or outcomes.