Significats de hepatic specification en anglès

In conclusion, the present results suggest that HHEX promotes hepatic specification by repressing EOMES expression.

Furthermore, EOMES exerts its effects downstream of HHEX in hepatic specification from the DE cells.

To reveal the molecular mechanisms of hepatic specification by HHEX, we tried to identify the genes directly targeted by HHEX.

While the signaling pathways involved in hepatic specification are well understood, the mechanisms through which FGFs induce hepatic character within the endoderm are ill defined.