Significats de high binding en anglès

Exploiting this knowledge, mannosides with extraordinarily high binding affinities have been designed.

Results: LY2795050 displays full antagonist activity and high binding affinity and selectivity for KOR.

The high binding versatility of Site-Y or the considerable stiffness of Site-X tune TFAM interactions.

A number of these new compounds show a high binding affinity for D3R with excellent selectivity.

Results: Three candidate peptides were characterized from eight phage clones with high binding affinity for sAPRIL.

Using a high binding MaxiSorp plate, we were able to eliminate the need for the capture antibody.

The relative orientation of these two rings is also important for high binding affinity to the DAT.

All of the compounds showed high binding affinities for the DAT in the low to subnanomolar range.

A total of 17 compounds were evaluated, revealing molecules with both high binding affinity and BBB permeability.

Results revealed that among Khat constituents βSitosterol showed high binding affinity towards 17β-HSD5.

CgDM9CP-1 was found to exhibit high binding specificity and avidity toward d-mannose residue.

Polycyclic aromatic compounds were related to the number of rings, showing high binding effects to chemical structures with triple rings.

Affinity maturation is an important part of the therapeutic antibody development process as in vivo activity often requires high binding affinity.

An important goal in drug development is to engineer inhibitors and ligands that have high binding affinities for their target molecules.

Collectively, these data provide an example where very high binding affinity is achieved through the cumulative effect of many small structural alterations.

Agreement was excellent, especially when the samples showing very high binding (greater than 600 fmol per milligram of protein) were excluded.