Significats de human postmortem en anglès

Mixed pathology is common and multiple different protein aggregates are seen in human postmortem brains.

A method for processing human postmortem material for application of autoradiography to large cryosections is described.

Ten human postmortem brains were scanned using an MRI 3-D FLASH sequence prior to histological processing.

Here, we describe the successful application and optimisation of 2-D DIGE technology for human postmortem brain studies.

Area-specific cytoarchitectonic patterns were studied in serial histological sections stained for cell bodies of ten human postmortem brains.

Our results demonstrate that PSD fractions can be isolated from human postmortem brain tissues with a reasonable degree of integrity.

We have investigated the influence of apoE genotype on neuronal cell dendritic spine density in mice and in human postmortem tissue.

All three methods separated fractions from human postmortem brains that were highly enriched in typical PSD proteins, almost to the exclusion of pre-synaptic proteins.

Consistent with human postmortem findings, we found that Kal9-P2255T protein levels were higher than those of wild-type Kal9 in neurons.

We examined these fractions using electron microscopy (EM) and verified the integrity of the synaptic membrane and PSD fractions derived from human postmortem brain tissues.

Human postmortem lung tissue, human blood-derived macrophages, and pulmonary microvascular endothelial cells.