Significats de hydrophobic core en anglès

The inter-domain allosteric effect is likely mediated by the flexibility in the hydrophobic core.

The comparisons show a highly conserved hydrophobic core and conservation of a few key residues.

Unfolding started with the melting of C-terminal strands, leading to exposure of the hydrophobic core.

The structural stability of the recognition site is maintained by the hydrophobic core and hydrogen bonding network.

Its hydrophobic core attracts certain volatile aromas-likeof rancid grease -andtraps them inside its funnel shape.

The regions flanking the leucine-zipper-like layers contain a hydrophobic core similar to that of more general four-helix-bundle proteins.

The calix conjugate further provides a hydrophobic core in assisting the diffusion of hydrophobic substrates toward catalytic sites.

Using this strategy, the key NOEs that define the hydrophobic core and overall fold of the protein are easily obtained.

The three-dimensional structure indicates that all conserved hydrophobic residues are in the hydrophobic core and therefore may be important for structural integrity.

To our surprise, increasing the hydrophobicity of residue 256 within the hydrophobic core of the enzyme resulted in a lower thermal stability.

Rearrangement of the hydrophobic core appears to be a common mechanism by which GPCRs and GEMs activate G proteins, although with different efficiency.

We present results from all-atom, fully unrestrained ab initio folding simulations for a stable protein with nontrivial secondary structure elements and a hydrophobic core.

These helices strongly interact hydrophobically with the corresponding helices of the other subunit to form a hydrophobic core at the center of the dimer.

This translocation of lipid II must be assisted by flippases thought to shield the disaccharide-pentapeptide as it crosses the hydrophobic core of the membrane.

Here we report the gating cooperativity in trimeric and tetrameric Hv channels engineered by altering the hydrophobic core sequence of the coiled-coil assembly domain.

A mutant that created a cavity in the hydrophobic core of the thermophilic enzyme was designed to investigate the importance of packing density for thermostability.