Moreover, the structure highlights the presence of a water molecule interacting with the hydroxygroup of the substrate and potentially involved in catalysis.
2
Because doxercalciferol does not have a 25- hydroxygroup, it requires 25-hydroxylation by the liver to be activated, a process independent of kidneys.
3
It is shown that replacement of the 4- hydroxygroup of lead compound 1 with a methylamine group results in a significant 6-fold increase in affinity.
4
Hydroxygroups in the sucrose will make the resin friable.
5
The hydroxygroups were mainly introduced at the respective equatorial hydrogen atoms at the 4'-carbon of trans-OH and the 5'-carbon of cis-OH.