Significats de hypoxanthine en anglès

In the purine pathway, significant reductions in hypoxanthine and xanthine levels were observed.

Oxygen radicals were generated by hypoxanthine and xanthine oxidase.

There was no significant effect on the growth rate or the intracellular nucleotide pools with hypoxanthine-treated cells.

Main outcome measures: Blood lactate, ammonia, and hypoxanthine levels were measured during exercise with expired gas analysis.

On the other hand, secretion of uric acid was relatively higher than xanthine and hypoxanthine in mWAT.

Our data indicate that losartan induces a significant decrease in the urinary excretion of hypoxanthine without changes in xanthine.

Absent release of these markers is not consistent with an association between ischemic hypoxanthine accumulation and postreperfusion oxidative stress.

The mutation frequency in Chinese hamster ovary cells at the hypoxanthine-guanine phosphoribosyltransferase locus was measured using resistance to 6-thioguanine.

A simultaneous oral administration of febuxostat and inosine was reported to elevate both hypoxanthine and ATP levels in peripheral blood.

Moreover, cells were capable of growth in either hypoxanthine-aminopterin-thymidine or G418, even in the absence of direct selection for this activity.

Determination of adenine, hypoxanthine, guanine and xanthine in different parts of pork and beef using high performance liquid chromatography was described.

The presence of an amino group at position 8 of the hypoxanthine moiety stabilizes the triplex but, surprisingly, destabilizes the duplex.

Conclusions: The present study revealed that hypoxanthine was secreted from human adipose tissue, and the secretion might be increased in local hypoxia.

PMID: 30631120 A simultaneous oral administration of febuxostat and inosine was reported to elevate both hypoxanthine and ATP levels in peripheral blood.

The effects of intra-arterial and intravenous injections of adenosine and hypoxanthine were investigated with special reference to respiratory variables in anesthetized young cats.

Beer-induced increases in plasma concentration and urinary excretion of hypoxanthine in the combination study were markedly higher than those in the beer-only study.