Significats de imidazole en anglès

We applied the approach to study minor groove binding of diamidines and pyrrole-imidazole polyamides.

This value agrees with the protonation of an imidazole group.

We furthermore demonstrated that imidazole has an inhibitory role at high concentrations used in crystallization.

Spin coupling to the nitrogen of a coordinated histidine imidazole was observed for both metals.

Further, both nicotinic acid and imidazole inhibited the degree of LES relaxation produced by esophageal distension.

However, the presence of the carbene doubles the catalytic activity of the mutant compared to the imidazole variant.

One of the methyl groups of the tert-butyl group of N-tert-butyl-2-thio-imidazole is disordered between two equally populated positions.

A second imidazole bound by Tyr394 and Thr212 was identified in the substrate channel.

This showed that the release of polyplexes from the surface by imidazole and EDTA was necessary for cell uptake.

Treatment with 5-amino-4-imidazole carboxamide riboside ameliorated cardiac architecture derangement in mice of both ages.

Involvement of the imidazole moiety of the His-6 residue has been demonstrated by the pH dependence of the NMR observables.

These interactions, together with desolvation effects, contribute to significantly depress the pKa of the buried imidazole ring in the native state.

Metabolites correlating with lower microbial diversity included glutarate and imidazole propionate, of which the latter has been implicated in insulin resistance.

The products generated using N-centered nucleophiles can be further transformed to important classes of organic molecules such as benzocarbazole and imidazole derivatives.

We prepared novel 1,2,4,5-tetrasubstituted imidazole derivatives with high anti-inflammatory activity by using our previously described regiospecific synthesis.

This effect was partly reversed at acidic pH in the K56H mutant likely due to protonation of the imidazole ring of the histidine.