Significats de immortalize human en anglès

The HPV-transforming gene E7 was unable to immortalize human mammary epithelial cells.

Although HTLV-1 can immortalize human lymphocytes in culture, identification of molecular events leading to tumorigenesis after HTLV-1 infection remain elusive.

Up-regulation of CD20 following Myc inactivation was also observed in immortalized human lymphocytes.

Methods Immortalized human chondrocytes were developed for studying responses to cytokines and prostaglandins.

Interestingly, the drugs had no effect on endogenous p53 in two immortalized human cell lines.

The ARAF mutations were shown to transform immortalized human airway epithelial cells in a sorafenib-sensitive manner.

We have studied the consequences of expression of v-cyclin in primary and immortalized human dermal microvascular ECs.

Epstein-Barr virus- immortalized human lymphocytes were used to analyze the transition from the benign hyperproliferative to the malignant transformed state.

An attractive in vitro model has been developed for the direct assessment of cell transport, using the immortalized human epithelial cell line, Caco-2.

We demonstrate that EGFR activation markedly alleviated the requirement of matrix engagement for survival of primary and immortalized human keratinocytes in suspension culture.

Objective: To develop a reproducible immortalized human chondrocyte culture model for studying the regulation of chondrocyte functions relevant to arthritic diseases in adult humans.

We used expression profiling of an immortalized human prostate epithelial cell line to identify 205 androgen-responsive genes (ARGs), most of them novel.