Significats de indian hedgehog en anglès

Background: Intestinal epithelial cells express the Sonic and Indian hedgehog ligands.

However, an absence of Indian hedgehog expression which occurs in WT cells was found.

We show that Indian Hedgehog, a bone-derived signaling molecule, participates in growth of skeletal muscle.

Conditional ablation of Indian hedgehog (Ihh) in the murine uterus results in mice that are sterile because of defects in embryo implantation.

Moreover, phosphorylation of p38 MAP kinases is greatly reduced and expression of a key regulator of cartilage development, Indian hedgehog, is increased in mutant mice.

Here, we elucidate that Indian hedgehog, a secreted ligand important for fetal development, is a crucial mediator of the regenerative acceleration triggered by ALPPS surgery.