Significats de induce er en anglès

In both alcohol and non-alcohol- induced ER stress, a common candidate is hyperhomocysteinemia.

In the latter, a key candidate for inducing ER stress is hyperhomocysteinemia.

Taken together, our study demonstrated that hypertension induced ER stress after Ang II infusion.

We demonstrated that IL-17A induced ER stress in macrophages and thus promoted inflammation in vitro.

Mechanistically, IL-17 augmented alcohol- induced ER stress in isolated crypts.

Caspase-12 induced ER stress involves in hepatocyte apoptosis.

However, the relationship between HCV- induced ER stress and UPR activation with TGF-β1 production has not been fully characterized.

In this study we found that radiation can induce ER stress and downstream signaling associated with the ERSR.

In contrast, knockdown of SREBP-1c or glycerol-3-phosphate acyltransferase 1 augmented PA- induced ER stress responses.

NS1 expressed in the ER lumen induced ER perinuclear aggregation with an ultrastructure resembling that of the replication compartment.

We hypothesized that inducing ER stress in the mammalian brain in vivo would trigger or exacerbate mutant torsinA-induced dysfunction.

However, whether the breast cancer cells with induced ER alpha restore response to endocrine therapy requires to be further researched.

Taken together, our results suggest that agents that induce ER stress may enhance TRAIL-R2 expression and increase the therapeutic response to TRAIL in melanoma.

In mammalian cells, CHK1 was activated by agents that induce ER stress, which resulted in a G2 cell cycle delay.

Using a small molecule inhibitor, we determined that AP-1 was required for Gnrh1 repression by high-dose palmitate or tunicamycin- induced ER stress.

The ability of bortezomib to induce ER stress and the unfolded protein response was investigated in a human pancreatic cancer cell line, L3.6pl.