Significats de induce ph en anglès

A recent study showed that deficiency of Cyp2j did not protect male and female mice from hypoxia- induced PH.

In this study, we test the hypothesis that ARC expression is essential for the development of chronic hypoxia- induced PH.

Exercise- induced PH is caused either by pulmonary vasoconstriction, pulmonary vascular remodeling, or by increased upstream transmission of pulmonary venous pressure.

Paradoxically and unexpectedly, we found that Cyp2c44 disruption exacerbated hypoxia- induced PH in female but not male mice.

Our data suggest that vascular smooth muscle-derived IGF-1 plays a critical role in hypoxia- induced PH in neonatal mice but not in adult mice.

Since CYP2C44 is a functionally important epoxygenase, we hypothesized that knockout of the Cyp2c44 gene would protect both sexes of mice from hypoxia- induced PH.