Significats de induce senescence en anglès

Moreover, some chemotherapeutic protocols induce senescence in tumour cells and, consequently, senescence markers could help to monitor treatment response.

Treatment with either Aβ1-42 monomer or Aβ1-42 fibrils did not induce senescence in this assay.

Retinoids induce senescence-like growth arrest in MCF-7 breast carcinoma cells; this effect is associated with the induction of several growth-inhibitory genes.

Radiation can induce senescence in many organs and tissues; however, it is still unclear how radiation stimulates senescence in mouse small intestine.

In summary, our study suggested that total body irradiation may induce senescence in the small intestine and damage the health status of the irradiated mice.

Immunity- induced senescence triggers a stable cell cycle arrest of cancer cells.

Here we investigate the role of caveolin-1 in bleomycin- induced senescence.

Here we show that oncogene- induced senescence occurs in otherwise normal murine hepatocytes in vivo.

Oncogene- induced senescence can provide a protective mechanism against tumour progression.

Here, we show that SETD1A supports mitotic processes and consequentially, its knockdown induces senescence.

Oxidative stress (OS)- induced senescence of the amniochorion has been associated with parturition at term.

Suppression of RPIA inhibits proliferation only in p16-low cells by inducing senescence both in vitro and in vivo.

In this review, we summarize some of the key findings in the field of senescence, stress- induced senescence and telomeres.

Oncogene- induced senescence (OIS) is thought to be a barrier to malignant transformation resulting from the strong activation of oncogenes.

As a result, the mTERT-mediated telomerase activity and telomere maintenance are responsible for the protective effect of Zfp637 against oxidative stress- induced senescence.

Using the human immortalized primary cells, HBx was found to retain the ability to overcome active oncogene RAS- induced senescence that requires full-length HBx.