Significats de involve in substrate en anglès

The model also predicted that His-171 in hGH may be involved in substrate binding.

Despite recent functional studies, the mechanisms involved in substrate recognition and selective ubiquitination of its binding partners remain elusive.

In addition, they encompass five other conserved motifs some of which may be involved in substrate (NTP) binding.

Homology modeling suggests that Lys76 may also be involved in substrate binding, and this postulate is supported by mutagenesis studies.

This mutation pinpoints a previously unknown, functionally critical feature of factor IX which may be involved in substrate or co-factor binding.

Neither domain of these proteins has a full set of the residues involved in substrate binding and catalysis in other GCHIs.

We have introduced mutations around the groove, and have identified residues involved in substrate specificity, single-stranded DNA binding and deaminase activity.

The enzyme is built up of three domains, a FAD-binding domain, a domain involved in substrate binding, and a C-terminal thioredoxin-like domain of unknown function.

PPARa and PPARδ are highly expressed in oxidative tissues and regulate genes involved in substrate delivery and oxidative phosphorylation (OXPHOS) and regulation of energy homeostasis.

A comparison of APOBEC3G-CD2 with other deaminase structures shows a structural conservation of the active-site loops that are directly involved in substrate binding.