Significats de isogenic cells en anglès

Gene expression activity is heterogeneous in a population of isogenic cells.

Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cell state.

With progress in genome editing and somatic cell nuclear transfer, it is theoretically possible to obtain genetically repaired isogenic cells.

Here, we study the differences in kinase requirements among various human cells, including freshly prepared primary cells, isogenic cells, immortalized cells, and cancer cell lines.