Significats de l-citrulline en anglès

Objective: To evaluate the benefits and harms of a combination of l-citrulline and metformin treatment among patients with DMD.

The importance of l-arginine during infection is supported by the finding that inhibiting its synthesis from its precursor l-citrulline blunts host defense.

Additional studies were performed to evaluate SNAT protein expression and l-citrulline levels in lungs of piglets with chronic hypoxia-induced pulmonary hypertension and comparable age controls.

During the first few weeks following pulmonary mycobacterial infection, we found a drastic increase in l-citrulline in the lung, even though serum concentrations were unaltered.

Fractional shortening was decreased and myocardial L-citrulline was increased in infected WT mice.

PMID: 10960632 Plasma levels of L-citrulline and L-arginine were measured by using high-performance liquid chromatography.

NO and L-citrulline formation by both enzymes were calcium-independent and inhibited by NG-nitro-L-arginine and NG-methyl-L-arginine.

In conclusion, L-citrulline supplementation reduced respiration rate of lactating sows and reduced piglet pre-weaning mortality rate in summer.

Metformin, L-citrulline or their combination did not alter serum nitrite and nitrate concentrations and their urinary excretion rates.

L-Citrulline supplementation resulted in considerable increase of the concentrations of amino acids and creatinine in the serum, and in their urinary excretion rates.