Significats de laminar fate en anglès

Here we asked whether these proneural genes also regulate laminar fate transitions.

Less well understood is how laminar fate transitions are regulated in cortical progenitors.

We found that the transcription factor AP2gamma regulates laminar fate in a region-specific manner.

Conversely, a reduction in GSK3 activity promotes the precocious differentiation of later stage cortical progenitors without influencing laminar fate specification.

Neurons expressing these factors are generated at characteristic developmental times, and have specific laminar fates within the tectum.