Significats de leading to atherosclerosis en anglès

Background and aims: Endothelial senescence is an important risk factor leading to atherosclerosis.

Objective: Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors leading to atherosclerosis and diabetes.

Compelling evidence points to oxidative stress as an important trigger in the complex chain of events leading to atherosclerosis.

Among the pathogenetic factors leading to atherosclerosis, the role of insulin resistance and hyperinsulinemia as independent risk factors is still under debate.

Since endothelial dysfunction is a factor leading to atherosclerosis, this abnormality may partly explain predisposition of patients with thyroid failure to cardiovascular disease.