Despite several reports of linked loci, major gene identification has been elusive.
2
In addition, we identified MOBP and SCFD1 as new associated risk loci.
3
Linkage analysis is used to map genetic loci using observations on relatives.
4
Risk loci in several populations have been identified with genetic linkage analysis.
5
However, the effects that we observe are subtle and variable between loci.
1
Impact: These findings may help to identify geneticregions associated with IMPC risk.
2
This study aimed to determine the geneticregions associated with strain effects on lesion area.
3
In particular, the oldest pre-epidemic isolates carry phage-associated geneticregions not previously reported in S. Enteritidis.
4
The genomic positions of recombinant and mobile geneticregions were partially linked, suggesting their concurrent occurrence.
5
Further research on these geneticregions will enhance our understanding of the genetic basis of natural menopause.
1
Pathogenicity is restored to wild-type levels in strains with reconstitution of the genomiclocus.
2
Hence, CAPTURE provides a versatile platform to study genomiclocus-regulating chromatin composition in a mammalian genome.
3
To facilitate both gene-specific and systems biology oriented research, our database provides the means to analyze individual genes or an entire genomiclocus.
4
We further observed Firre localization across five distinct trans-chromosomal loci, which reside in spatial proximity to the Firre genomiclocus on the X chromosome.
1
Their ability to readily manipulate the native genomicloci is particularly advantageous.
2
However, processing different databases and searching among millions of genomicloci is not trivial.
3
Currently miRBase is their primary repository, providing annotations of primary sequences, precursors and probable genomicloci.
4
Pseudo-polyploidy at relevant genomicloci sets the stage for gaining additional mutations at the locus of interest.
5
This study was aimed at identifying the genomicloci linked to exercise participation in males and females.
1
The aim of the study is detection of Y-sequences of DNA level, calculation of mosaicism and its cytogeneticlocation.
1
Here, we report the nucleotide sequence and chromosomallocus of the mouse Hes-3 gene.
2
Homozygosity mapping with SNPs was performed for identification of the chromosomallocus for the disease.
3
These molecules undergo homologous recombination with the corresponding chromosomallocus to generate targeted alterations of the host genome.
4
Linkage to the chromosomallocus 13q31-q32 has previously been reported in a large French family.
5
Herein, we identified a novel TAL1-regulated super-enhancer controlling the GIMAP locus, which resides within an insulated chromosomallocus in T-ALL cells.
1
There is no specific ultrasound prenatal diagnosis and no identified geneticlocus.
2
The broad geneticlocus heterogeneity renders mutation screening time-consuming and expensive.
3
Conclusion: We report identification of a geneticlocus for familial mesial temporal lobe epilepsy.
4
This geneticlocus may contain determinants that play a crucial role in male gametogenesis by P. falciparum.
5
To our knowledge, this is the first genome-scan report to identify a geneticlocus harboring a gout-susceptibility gene.
1
Linkage analysis is used to map geneticloci using observations on relatives.
2
A GWAS meta-analysis identified 68 geneticloci controlling platelet size and number.
3
Previous studies have identified many geneticloci for refractive error and myopia.
4
For most geneticloci which have been tested, there have been inconsistent results.
5
We aimed to identify geneticloci that are associated with bone mineral density.
1
DNAloci that interact with the target RNA are identified using high-throughput DNA sequencing.
2
In gene regulation, proteins function as members of protein complexes to recognize chromosomal target DNAloci.
3
These findings suggest that longevity is partly determined by epistatic interactions involving these three mt DNAloci.
4
We have developed a measure of genetic distance, DSW, which is appropriate for the analysis of highly polymorphic DNAloci.
5
A marked variation in number and localization of r DNAloci but no correlation between the numbers of rDNA clusters and genome size was found.