Change in morphology and behavior of a macrophage, resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1However, the antigens that induce macrophage activation have not been well defined.
2These results demonstrate that a galectin-3 feedback loop drives alternative macrophage activation.
3The mechanisms that regulate macrophage activation in chronic inflammation are poorly understood.
4Increased galectin-3 expression and secretion is a feature of alternative macrophage activation.
5Our results suggested that macrophage activation and differentiation were necessary for virus reactivation.
6Bone marrow studies established the diagnosis of macrophage activation syndrome with active hemophagocytosis.
7These protective effects are exerted by inhibiting inflammation, fibrosis, and reducing macrophage activation.
8High salt also potentiated lipopolysaccharide-induced macrophage activation and suppressed interleukin 4-induced macrophage activation.
9The enzyme chitotriosidase can be assayed to quantify the degree of macrophage activation.
10Appropriate regulation of macrophage activation is essential for pathogen clearance or preventing autoimmune diseases.
11We have examined the role of tyrosine phosphorylation during the course of macrophage activation.
12This might contribute to the increased incidence of macrophage activation syndrome in these patients.
13Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity.
14Hepatic patterns of macrophage activation were explored with immunohistochemistry.
15However, little is known about the function and mechanism of action of miR-125b in macrophage activation.
16Although Notch signaling participates in various aspects of immunity, its role in macrophage activation remains undetermined.
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