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1 Imperial Sugar had already weathered some major challenges - bankruptcy, divestiture, new management.
2 While this enhances models' usefulness in prediction and policy, major challenges remain.
3 One of the major challenges in neurodegenerative research is modeling systemic aging.
4 Rarity, chronicity and complexity of diseases are major challenges to PR care.
5 Motion-related artifacts are one of the major challenges associated with pediatric neuroimaging.
6 Finally, the perspectives and major challenges of microorganism-derived ester synthesis are presented.
7 I think it was all fairly…well…it didn't throw up any major challenges .
8 Surgeons face major challenges in achieving curative R0 resection for pancreatic cancers.
9 The country has major challenges in terms of unemployment, crime and government inefficiency.
10 Future research directions and remaining major challenges in this field are also outlined.
11 All of this change poses major challenges for Irish and global education systems.
12 The BBC Innovators series looks at solutions to major challenges across South Asia.
13 She said that Aer Rianta was facing major challenges and opportunities.
14 Some will grapple with major challenges , others can look forward to huge opportunities.
15 We had some pretty major challenges to confront, Mr Cull said.
16 High costs, cheap imports and little State support provide major challenges .
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