Significats de mediate cleavage en anglès

MicroRNAs produced by Dicer mediated cleavage of RNA hairpins contribute to gene regulation by posttranscriptional silencing.

Tryptophan acts by inhibiting Release Factor 2- mediated cleavage of this peptidyl-tRNA at the tnaC stop codon.

Our data raise the possibility that the pro-apoptotic role of PICOT is actively regulated via caspase-3- mediated cleavage.

We hypothesized that HOCl would oxidize either or both of these residues and possibly inhibit ADAMTS13- mediated cleavage.

FLAG provides real-time signal generation during PCR by PspGI- mediated cleavage of quenched fluorophores at the 5' end of double-stranded PCR products.

These results suggest that an activated bleomycin-Fe-O2 complex disrupts essential cell wall polymers in a manner analogous to bleomycin- mediated cleavage of DNA.

Quinolones promoted gyrase- mediated cleavage of plasmid pBR322 DNA due to stabilization of the cleavage complex, which is thought to be the lethal lesion.

The S-deoxy analog of 1 does not cleave DNA under conditions where 1 effects efficient thiol- mediated cleavage of DNA.

These results show that chemotherapy-induced apoptosis inhibits autophagy at the execution stage subsequent to cytochrome c release through caspase 8- mediated cleavage of Beclin 1.