Significats de mediate efflux en anglès

An increase in extracellular serotonin results from transporter- mediated efflux triggered by amphetamine-like psychostimulants.

Conclusion: Our study suggests that high triglyceride levels facilitate ABCA-1 mediated efflux function of HDL in part by activating CETP.

Additionally, HDL mediated efflux was measured in 13 diabetic and non-diabetic participants fasting and four hours after a high-fat test challenge.

Mutation of the latter resulted in a loss of amphetamine-induced SERT- mediated efflux and currents, as well as a lack of PIP2-dependent effects.

The estimated Vmax values for cyclodextrin- mediated efflux were 3.5-70-fold greater than for HDL3 for the three cell lines.

Therefore, we hypothesize that transporter- mediated efflux of testosterone precursors out of MA-10 cells is inhibited by TBBPA resulting in higher availability for testosterone production.