Significats de mediate neutralization en anglès

Antibody- mediated neutralization of NOX5-L attenuated tumor progression in a mouse xenograft model.

Consistent with this, ORF2S does not block HEV cell entry but inhibits antibody- mediated neutralization.

Absence of all four glycosylation sites rendered a primary isolate sensitive to CD4i antibody- mediated neutralization.

We found that the gp120-binding antibody population mediated neutralization of some isolates, but not all.

Thus, carbohydrates that flank receptor-binding regions on gp120 protect primary HIV-1 isolates from antibody- mediated neutralization.

During natural infection, gp120 is a primary target of the humoral immune response, and it has evolved to resist antibody- mediated neutralization.

Further, genetic knockdown and antibody- mediated neutralization of uPA have been shown to be protective against induction or progression of arthritis in animal models.

The rapid isolation of large panels of novel human neutralizing antibodies promises to reveal new insights into the fundamental principles underlying antibody- mediated neutralization of HIV.

Evaluation of antibody- mediated neutralization was possible at 2 to 3 days postinfection, at a time when p24 readouts were not conclusive.

Methods: The breadth of antibody- mediated neutralization against 11 tier 2 or 3 viruses was assessed in 163 clade B spontaneous controllers of HIV.