Significats de mediate resistance en anglès

The biological pathways that mediate resistance are unknown.

These findings demonstrate that MIF-induced early DC maturation and IL-12 production mediate resistance to T. gondii infection.

Natural killer (NK) cells are innate immune cells that mediate resistance against viruses and tumors.

These cells accumulate at the site of infection and in many cases can mediate resistance to these large multicellular pathogens.

We found 11 lncRNA loci that, upon recruitment of an activator, mediate resistance to BRAF inhibitors in human melanoma cells.

We concluded that OPNc or OPNb overexpression in PC3 cells can mediate resistance and cell survival features in response to DXT-induced cell death.

Important insights have recently been gained in our understanding of how host immune responses mediate resistance to parasitic helminths and control associated pathological responses.

Mechanisms that mediate resistance to anti-EGFR therapies include the presence of redundant tyrosine kinase receptors, increased angiogenesis, and the constitutive activation of downstream mediators.

These experiments support the concept that CD3- prototypical NK cells mediate resistance to NK cell-sensitive viruses via a mechanism independent of antiviral or "natural" antibody.

This points to the existence of an evolutionarily conserved and phytohormone-independent MLA1- mediated resistance mechanism.

The current study finds that plant-derived inhibitors can be an option towards restraining efflux- mediated resistance.

We also demonstrate that the autophagy was involved in SPARC expression mediated resistance to cisplatin.

In addition, this single-factor- mediated resistance is active against all known physiological races of the parasite.

Met is transactivated by EGFRvIII and plays a key role in EGFRvIII- mediated resistance to targeted treatment.

However, despite the extensive use of this locus, little is known about the mechanism of Rpv3- mediated resistance.

Emerging evidence suggests that this metabolic reprogramming also mediates resistance to the standard-of-care therapies used to treat GBM.