Significats de microbial antigens en anglès

The magnitude of responses to microbial antigens was examined according to variant status.

Summary: The intestine is continuously exposed to dietary and microbial antigens.

The immune system cannot reasonably be expected to selectively recognize microbial antigens and ignore mHA.

Live attenuated or genetically manipulated bacteria expressing other microbial antigens have been used for selective colonization of GALT.

Toll-like receptors (TLRs) act as sensors for microbial antigens and can signal via the MAPK pathway.

Impaired exclusion of microbial antigens can lead to chronic immunological activation which can affect the tolerance to self components.

Conclusions: Patients with Crohn's disease and unaffected relatives carrying variants of the NOD2 gene have increased adaptive immune responses to microbial antigens.

Importantly, serum antibodies against microbial antigens or auto-antigens have been used as biomarkers in predicting disease course, complications and responses to medications and surgery.

To study MR1-restricted T cell clones in the context of unique bacterial infection, we have generated a tetramer of MR1 loaded with diverse microbial antigens.