Significats de mitochondrial metabolism en anglès

Hypoxia is a feature of IBD and modulates cellular and mitochondrial metabolism.

These changes were accompanied by the activation of molecular targets controlling mitochondrial metabolism.

Little is known about interactions between both viruses on mitochondrial metabolism.

However, the relationship between OPA1 and mitochondrial metabolism and the underlying mechanisms remain unclear.

This study tested whether humans with NAFLD have abnormal in vivo hepatic mitochondrial metabolism.

Here we review recent studies on insulin action and the mechanistic association with mitochondrial metabolism.

Conclusion: HCV has deleterious effects on liver mitochondrial metabolism, notably on respiratory chain complex IV.

ERRγ directly regulates mitochondrial metabolism but cooperatively controls renal reabsorption via convergent binding with HNF1β.

Targeting mitochondrial dynamics can alter mitochondrial metabolism, and many current therapies already non-specifically affect mitochondrial dynamics.

Metabolic heterogeneity is defined as high mitochondrial metabolism in some tumor cells and glycolysis in others.

Inhibitors of mitochondrial metabolism are being developed for the treatment of solid organ and hematologic malignancies.

The cause and consequences of mild impairment of mitochondrial metabolism is one focus of this review.

In this Perspective, we highlight recent developments in targeting mitochondrial metabolism for the treatment of cancer.

This article is part of a Special Issue entitled: VDAC structure, function, and regulation of mitochondrial metabolism.

These data indicate hyperglycaemia induces metabolic changes in β-cells that markedly reduce mitochondrial metabolism and ATP synthesis.

Moreover, reactive oxygen species-induced mitochondrial metabolism and nutrient availability are important for interaction with tumor microenvironment components.