Significats de molecular chaperone en anglès

HSP70 is a molecular chaperone and a key component of the heat-shock response.

The molecular chaperone Hsp90 is a hub of protein homeostasis and regulatory circuitry.

The main target of these drugs is the molecular chaperone heat shock protein 90.

An intricate network of molecular chaperone proteins regulates CFTR's proper maturation and trafficking to the apical membrane.

A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90.

DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress.

We previously established that the molecular chaperone Hsp90 enables the emergence and maintenance of fungal drug resistance.

Here we implicate the molecular chaperone Hsp90 as a key regulator of biofilm dispersion and drug resistance.

HPrxI is a dual function protein, since it can behave either as a peroxidase or as a molecular chaperone.

We found that QPCT inhibition induced the levels of the molecular chaperone aB-crystallin and reduced the aggregation of diverse proteins.

The GroE proteins of Escherichia coli are heat shock proteins which have also been shown to be molecular chaperone proteins.

Finally, we report the crucial underlying role of the intranuclear heat shock protein 90 molecular chaperone complex in pulsatile GR regulation.

Despite this, the actual function that HSP90s conformationally-coupled ATPase activity provides in its biological role as a molecular chaperone remains obscure.

The functional expansion obtained through our finding establishes NPfA as a novel class of ATP-independent molecular chaperone with immense future biotechnological applications.

In this, the role of the molecular chaperone Hsp60 is unclear since it has been reported that it can be both, pro- or anti-apoptotic.

GRP94 is a molecular chaperone that carries immunologically relevant peptides from cell to cell, transferring them to major histocompatibility proteins for presentation to T cells.