Strategies using more immunogenic influenza vaccines must be evaluated in such patients.

Vaccines against major causes of diarrhea may be feasible, but likely need to be more immunogenic than natural infection.

Mice developed better antibody responses against C and R polypeptides, whereas the N polypeptide was more immunogenic in monkeys.

The more native-like the conformation of the aggregated proteins, the more immunogenic the preparations were in the transgenic mice.

In participants who had not previously received H5 vaccine, low-dose Anhui vaccine plus adjuvant was more immunogenic compared with higher doses of unadjuvanted vaccine.

The currently available anthrax vaccine requires a lengthy immunization schedule, and simpler and more immunogenic options for protection against anthrax are a priority for development.